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Omicron poses a grave risk to the US health care system. The US has a low rate of vaccination and obtaining boosters, and a relatively large segment of our population is elderly or immunocompromised. A 2-dose mRNA vaccine's immunity appears to rapidly wane and unlike South Africa, many in the US were fully vaccinated very early in the pandemic.

Only a small percentage of the Omicron variant of COVID-19 cases require hospitalization so far, but high infectivity may turn this small percentage into a large number of patients, which will further stress our health care system.